CasTLE

BEASTIE (Bayesian Estimation of Allele-Specific Transcription Integrating Expression) — statistical framework for detecting allele-specific expression (ASE) from RNA-seq data. Uses a Bayesian hierarch

1 shared topic • 2 shared operations

Use when working with GuacaMol — the benchmarking suite for de novo molecular generation — to evaluate generative models for drug-like molecules. Assesses distribution-learning (17 benchmarks: validit

1 shared topic • 2 shared operations

LocusZoom — regional association plot generator for GWAS and fine-mapping results. Creates publication-quality locus zoom plots showing -log10(p-value) vs genomic position with LD coloring, recombinat

1 shared topic • 2 shared operations

RASQUAL (Robust Allele Specific QUantification and quality controL) — joint QTL mapping tool that integrates total read counts and allele-specific reads for cis-regulatory variant discovery. Detects i

1 shared topic • 2 shared operations

ScreenProcessing — Python pipeline for analyzing pooled genetic screens (CRISPRi/CRISPRa). Converts raw FASTQ sequencing files into library counts using fastqgz_to_counts.py, then generates sgRNA phen

1 shared topic • 2 shared operations