ScreenProcessing

Forensic genetics — probabilistic genotyping, STR mixture interpretation, kinship and paternity analysis, population allele frequency databases, and NGS-based forensic sequencing. Covers R packages: f

3 shared topics • 1 shared operation

Use when performing Mendelian randomization (MR) analyses to estimate causal effects of exposures on outcomes using genetic variants as instrumental variables. Covers two-sample MR, IVW, MR-Egger, wei

3 shared topics • 1 shared operation

mpraprofiler — MPRA (Massively Parallel Reporter Assay) data analysis tool for quantifying regulatory element activity from barcode count tables. Normalizes DNA and RNA counts, computes activity ratio

3 shared topics • 1 shared operation

NgsRelate — pairwise relatedness estimation from NGS data using genotype likelihoods. Estimates kinship coefficients, R0/R1/KING-robust statistics, and inbreeding coefficients from VCF/BCF files or AN

3 shared topics • 1 shared operation

TRAPD — Toolkit for Rare variant Association from Population Data. Tests gene-level rare-variant burden in case-control studies using population databases (gnomAD, TOPMed) as controls. Implements adap

3 shared topics • 1 shared operation