MCScanX

MAGeCK-VISPR — comprehensive CRISPR screen analysis framework combining MAGeCK statistical testing (RRA and MLE algorithms) with VISPR interactive visualization. Supports sgRNA count generation from F

2 shared topics • 1 shared operation

NgsRelate — pairwise relatedness estimation from NGS data using genotype likelihoods. Estimates kinship coefficients, R0/R1/KING-robust statistics, and inbreeding coefficients from VCF/BCF files or AN

2 shared topics • 1 shared operation

Use when working with odgi — the optimized dynamic genome/graph implementation toolkit — for pangenome variation graph manipulation, sorting, visualization, and analysis. Converts GFA graphs to effici

2 shared topics • 1 shared operation

scikit-allel — Python package for exploratory analysis of large-scale genetic variation data. Provides data structures for genotypes, haplotypes, and allele counts (GenotypeArray, HaplotypeArray, Alle

2 shared topics • 1 shared operation

ScreenProcessing — Python pipeline for analyzing pooled genetic screens (CRISPRi/CRISPRa). Converts raw FASTQ sequencing files into library counts using fastqgz_to_counts.py, then generates sgRNA phen

2 shared topics • 1 shared operation