Use when performing Transcriptome-Wide Association Studies (TWAS) with TIGAR, a nonparametric Bayesian tool from Yang Lab for training gene expression prediction models and testing gene-trait associat
Use with AI
Install the MCP server or CLI to instantly fetch TIGAR documentation:
Install command
claude mcp add biocontext7 -- npx @biocontext7/mcpOr share this page: biocontext7.com/tools/tigar
Use when running Transcriptome-Wide Association Studies (TWAS) with FUSION, integrating GWAS summary statistics with precomputed eQTL expression weights to identify genes whose predicted expression is
1 shared topic • 3 shared operations
PredictDB builds elastic-net genetic prediction models of gene expression stored as SQLite .db files for use with PrediXcan, S-PrediXcan, and S-MultiXcan TWAS workflows. Use this skill for training ex
1 shared topic • 3 shared operations
Use when working with scPrediXcan — a TWAS (Transcriptome-Wide Association Study) framework that extends PrediXcan to single-cell resolution using sc-eQTL prediction models. Maps GWAS loci to cell-typ
1 shared topic • 3 shared operations
Bracken (Bayesian Reestimation of Abundance with KrakEN) — statistical method for computing species-level abundance estimates from Kraken/Kraken2/KrakenUniq taxonomic classifications. Redistributes re
1 shared topic • 2 shared operations
FINEMAP — Bayesian fine-mapping tool for identifying causal variants from GWAS summary statistics and linkage disequilibrium (LD) matrices. Uses shotgun stochastic search to enumerate causal configura
1 shared topic • 2 shared operations