mpraprofiler

ScreenProcessing — Python pipeline for analyzing pooled genetic screens (CRISPRi/CRISPRa). Converts raw FASTQ sequencing files into library counts using fastqgz_to_counts.py, then generates sgRNA phen

3 shared topics • 1 shared operation

TRAPD — Toolkit for Rare variant Association from Population Data. Tests gene-level rare-variant burden in case-control studies using population databases (gnomAD, TOPMed) as controls. Implements adap

3 shared topics • 1 shared operation

Use when working with bigsnpr — an R package for analysis of massive

3 shared topics

NgsRelate — pairwise relatedness estimation from NGS data using genotype likelihoods. Estimates kinship coefficients, R0/R1/KING-robust statistics, and inbreeding coefficients from VCF/BCF files or AN

3 shared topics

vt — C++ command-line variant tool set for manipulating VCF files. Provides variant normalization (left-alignment and trimming), multiallelic decomposition, VCF summary statistics (peek), annotation,

3 shared topics