DRAGEN Bio-IT Platform

Rcorrector — kmer-based error correction for RNA-seq reads. Corrects Illumina sequencing errors in FASTQ data using Jellyfish2 bloom filters and adaptive kmer frequency thresholds. Handles non-uniform

3 shared topics • 1 shared operation

Souporcell — genotype-based demultiplexing of pooled single-cell RNA-seq experiments. Assigns cells to donor of origin using SNP variants from the aligned BAM file without requiring known genotypes. D

3 shared topics • 1 shared operation

Use when working with CellRegMap — a Python framework for mapping context-specific genetic effects (sc-eQTL) in single-cell RNA-seq data. CellRegMap models genotype × cell-state interactions using a l

2 shared topics • 2 shared operations

Use when working with eQTL Catalogue — a uniformly processed, open-access resource of expression quantitative trait loci (eQTL) summary statistics from 100+ studies across bulk tissues, primary cell t

2 shared topics • 2 shared operations

Loom — HDF5-based file format and Python library (loompy) for storing and accessing large single-cell RNA-seq datasets. Supports sparse/dense matrices, row attributes (genes/features), column attribut

2 shared topics • 2 shared operations