Leafcutter — annotation-free RNA splicing quantification from short-read RNA-seq data. Detects differential intron usage, alternative splicing events, outlier splicing (LeafcutterMD), and splicing QTL
Use with AI
Install the MCP server or CLI to instantly fetch Leafcutter documentation:
Install command
claude mcp add biocontext7 -- npx @biocontext7/mcpOr share this page: biocontext7.com/tools/leafcutter
BPCells is a high-performance toolkit for large single-cell RNA-seq and ATAC-seq datasets. Use it when the user mentions BPCells, disk-backed sparse matrices, bitpacked single-cell storage, large 10x
2 shared topics • 2 shared operations
CellPhoneDB — repository of curated receptors, ligands, and their interactions for cell-cell communication analysis from single-cell RNA-seq data. Performs permutation-based statistical analysis (stat
2 shared topics • 2 shared operations
IsoformSwitchAnalyzeR — R/Bioconductor package for detecting, annotating, and visualizing isoform switches with functional consequences from RNA-seq data. Integrates with Salmon, kallisto, StringTie,
2 shared topics • 2 shared operations
PyDESeq2 — Python implementation of DESeq2 for differential gene expression analysis from bulk RNA-seq count data. Performs size factor normalization, genewise dispersion estimation, Wald tests with B
2 shared topics • 1 shared operation
RASQUAL (Robust Allele Specific QUantification and quality controL) — joint QTL mapping tool that integrates total read counts and allele-specific reads for cis-regulatory variant discovery. Detects i
2 shared topics • 1 shared operation