HPRC Tools

DAS Tool — genome-resolved metagenomics bin refinement tool that integrates results from multiple binning algorithms to produce an optimized, non-redundant set of metagenome-assembled genomes (MAGs).

1 shared topic • 2 shared operations

Ensembl Database — EMBL-EBI's comprehensive genome annotation database covering 300+ species with gene models, variants, regulatory features, and comparative genomics. Query via REST API at rest.ensem

1 shared topic • 2 shared operations

GATK HaplotypeCaller — germline short variant caller using localized de novo assembly of haplotypes. Calls SNPs and indels from BAM/CRAM alignment files, producing VCF or gVCF output. Supports single-

1 shared topic • 2 shared operations

Purge_dups — haplotypic duplication identification and removal tool for genome assemblies. Detects and removes overlapping haplotigs and heterozygous duplications from primary assemblies using read de

1 shared topic • 2 shared operations

SvABA -- structural variant and indel caller using genome-wide local assembly. Detects deletions, insertions, duplications, inversions, and complex rearrangements from short-read (Illumina) whole-geno

1 shared topic • 2 shared operations