vcflib

AGAT (Another Gff Analysis Toolkit) — comprehensive Perl toolkit for reading, writing, validating, fixing, and manipulating genome annotation files in GFF3, GTF, and GFF2 formats. Converts between for

1 shared topic • 2 shared operations

Limnology (freshwater science) — computational toolkit for freshwater ecosystem analysis including lake thermal stratification (rLakeAnalyzer), lake metabolism estimation (LakeMetabolizer), eDNA metab

1 shared topic • 2 shared operations

Use when performing GWAS fine-mapping with PAINTOR (Probabilistic Annotation INTegratOR). Computes posterior inclusion probabilities (PIPs) for causal variants by integrating summary statistics (Z-sco

1 shared topic • 2 shared operations

Use when working with PolyFun — functionally-informed polygenic fine-mapping from GWAS summary statistics. Computes per-SNP heritability priors using S-LDSC with functional annotations, then runs SuSi

1 shared topic • 2 shared operations

RTG Tools — Java-based toolkit from Real Time Genomics for haplotype-aware variant call comparison, VCF filtering, statistics, and pedigree analysis. Primary use: vcfeval for benchmarking variant call

1 shared topic • 2 shared operations