SMR (Summary-data-based Mendelian Randomization) for testing pleiotropic associations between molecular traits (eQTL, mQTL, sQTL) and complex traits using GWAS summary statistics. Includes HEIDI test
Use with AI
Install the MCP server or CLI to instantly fetch SMR documentation:
Install command
claude mcp add biocontext7 -- npx @biocontext7/mcpOr share this page: biocontext7.com/tools/smr
DMRcate — R/Bioconductor package for identifying differentially methylated regions (DMRs) from Illumina Infinium arrays (450K, EPIC, EPICv2) and whole genome bisulfite sequencing (WGBS/RRBS) data. Use
2 shared topics
LIMIX — Python library for linear mixed models (LMM) and interaction QTL (iQTL) mapping. Use for eQTL discovery, cis-QTL and trans-QTL scans, GxE interaction testing, conditional QTL analysis, and GWA
2 shared topics
methylKit -- R/Bioconductor package for DNA methylation analysis from bisulfite sequencing data. Reads Bismark, BSmap, and generic CpG coverage files. Provides differential methylation analysis at bas
2 shared topics
CmdStan — command-line interface to the Stan probabilistic programming language for Bayesian statistical modeling and high-performance inference. Compiles Stan programs (.stan) to C++ executables via
1 shared topic • 1 shared operation
PyStan — Python interface to Stan for Bayesian statistical modeling and high-performance inference. Compile Stan programs (stan.build), draw posterior samples via HMC-NUTS (model.sample), extract draw
1 shared topic • 1 shared operation