Use when registering or co-aligning multiplexed whole-slide images (WSI) from the same FFPE tissue section with different IHC or immunofluorescence stainings. Covers piecewise affine alignment of OME-
Use with AI
Install the MCP server or CLI to instantly fetch Palom documentation:
Install command
claude mcp add biocontext7 -- npx @biocontext7/mcpOr share this page: biocontext7.com/tools/palom
cryoSPARC — cryo-EM single particle analysis platform for high-resolution 3D structure determination. Provides motion correction, CTF estimation, particle picking (blob, template, Topaz), 2D classific
1 shared topic • 1 shared operation
Optogenetics skill for designing, analyzing, and interpreting light-based neural circuit manipulation experiments. Covers opsin selection (ChR2, halorhodopsin, Arch, C1V1, jRCaMP), viral vector strate
1 shared topic • 1 shared operation
QuPath — open-source platform for whole slide image analysis and digital pathology. Provides interactive tools for tissue detection via thresholding, cell detection and positive cell classification (H
1 shared topic • 1 shared operation
RELION — Bayesian approach to cryo-EM single-particle analysis for 3D structure determination of biological macromolecules. Provides motion correction, CTF estimation, particle picking (autopicking, L
1 shared topic • 1 shared operation
STARmap (Spatially-resolved Transcript Amplicon Readout mapping) — in situ spatial transcriptomics method that combines hydrogel-tissue chemistry with sequencing-by-hybridization (SEDAL) for multiplex
1 shared topic • 1 shared operation