NicheNet — R-based computational framework for studying intercellular communication from single-cell transcriptomics. Predicts which ligands expressed by sender cell types regulate target gene express
Use with AI
Install the MCP server or CLI to instantly fetch NicheNet documentation:
Install command
claude mcp add biocontext7 -- npx @biocontext7/mcpOr share this page: biocontext7.com/tools/nichenet
Use when working with Conos (Clustering On Network Of Samples), the R package for joint analysis of multiple single-cell RNA-seq and spatial transcriptomics datasets. Covers building joint k-nearest-n
2 shared topics • 2 shared operations
LIANA (LIgand-receptor ANAlysis) — unified Python framework for cell-cell communication inference from single-cell transcriptomics. Wraps multiple methods (CellPhoneDB, NATMI, Connectome, SingleCellSi
2 shared topics • 2 shared operations
pySCENIC — Python implementation of SCENIC for single-cell gene regulatory network inference and regulon analysis. Implements a three-step pipeline: GRN inference via GRNBoost2 or GENIE3, cis-regulato
2 shared topics • 2 shared operations
SCENIC (pySCENIC) — gene regulatory network inference and transcription factor regulon analysis for single-cell RNA-seq data. Infers TF-target gene networks using GRNBoost2/GENIE3, refines regulons vi
2 shared topics • 2 shared operations
STdeconvolve — reference-free cell-type deconvolution for spatial transcriptomics using Latent Dirichlet Allocation (LDA). Decomposes multi-cellular spatial pixels into cell-type proportions and trans
2 shared topics • 2 shared operations