mpralm is an R/Bioconductor package for differential activity analysis of Massively Parallel Reporter Assays (MPRA). It uses a limma-voom-style framework to compare RNA barcode counts to DNA barcode c
Use with AI
Install the MCP server or CLI to instantly fetch mpralm documentation:
Install command
claude mcp add biocontext7 -- npx @biocontext7/mcpOr share this page: biocontext7.com/tools/mpralm
PyDESeq2 — Python implementation of DESeq2 for differential gene expression analysis from bulk RNA-seq count data. Performs size factor normalization, genewise dispersion estimation, Wald tests with B
1 shared topic • 3 shared operations
Differential expression analysis for RNA-seq data using negative binomial generalized linear models with size factor normalization and empirical Bayes shrinkage.
1 shared topic • 2 shared operations
Use when performing differential gene expression analysis on RNA-seq count data using limma-voom. Covers the full workflow: count filtering with filterByExpr, TMM normalization via edgeR calcNormFacto
1 shared topic • 2 shared operations
MPRADesignTools — R package for designing Massively Parallel Reporter Assay (MPRA) experiments. Provides oligo library design, sample size estimation, barcode generation, sequence tiling, and statisti
1 shared topic • 2 shared operations
MSstats — Bioconductor R package for statistical analysis of quantitative mass spectrometry-based proteomics experiments. Supports label-free DDA, TMT, iTRAQ, SRM/MRM, and DIA workflows. Provides prep
1 shared topic • 2 shared operations