modkit — Oxford Nanopore Technologies Rust CLI for modified base (methylation) analysis on nanopore sequencing data. Processes modBAM files (BAM with MM/ML tags) to compute per-position modification f
Use with AI
Install the MCP server or CLI to instantly fetch modkit documentation:
Install command
claude mcp add biocontext7 -- npx @biocontext7/mcpOr share this page: biocontext7.com/tools/modkit
Fastq Screen — Perl tool for screening FASTQ sequencing reads against multiple reference genomes to detect sample contamination. Maps reads to user-defined genome databases (human, mouse, E. coli, Phi
2 shared topics • 1 shared operation
MethylDackel (formerly PileOMeth) -- fast C tool for extracting per-base methylation metrics from coordinate-sorted BAM/CRAM files produced by bisulfite sequencing aligners (Bismark, bwa-meth, BSMAP).
2 shared topics • 1 shared operation
Bismark — bisulfite-seq alignment and methylation calling toolkit. Maps bisulfite-treated reads to a reference genome using Bowtie 2, HISAT2, or minimap2, performs cytosine methylation calls in CpG/CH
2 shared topics
Use when working with bsseeker2 — BSseeker2 — bisulfite sequencing aligner
2 shared topics
dmrseq is an R/Bioconductor package for detecting differentially methylated regions (DMRs) from whole-genome bisulfite sequencing (WGBS) data. It fits a generalized least squares model with a smooth c
2 shared topics