GUIDES (Graphical User Interface for DNA Editing Screens) — web-based tool for designing customized CRISPR-Cas9 guide RNA libraries. Integrates Doench on-target efficiency scoring, tissue-specific gen
Use with AI
Install the MCP server or CLI to instantly fetch GUIDES documentation:
Install command
claude mcp add biocontext7 -- npx @biocontext7/mcpOr share this page: biocontext7.com/tools/guides
Dash Bio -- interactive bioinformatics visualization components built on Plotly Dash. Provides domain-specific charts including Circos plots, ideograms, needle plots (lollipop/mutation diagrams), alig
2 shared topics • 1 shared operation
Ensembl Database — EMBL-EBI's comprehensive genome annotation database covering 300+ species with gene models, variants, regulatory features, and comparative genomics. Query via REST API at rest.ensem
2 shared topics
gffread -- GFF/GTF utility for filtering, converting, and extracting sequences from genome annotation files. Converts between GFF3 and GTF formats, extracts transcript (FASTA) and protein sequences fr
2 shared topics
MAFFT — multiple sequence alignment for nucleotide and protein sequences. Implements progressive (FFT-NS-1, FFT-NS-2), iterative refinement (FFT-NS-i), and consistency-based iterative methods (L-INS-i
2 shared topics
OrthoFinder — fast, accurate ortholog inference for comparative genomics. Identifies orthogroups, orthologs, gene trees, rooted species trees, and gene duplication events from protein or nucleotide se
2 shared topics