demuxlet and freemuxlet (popscle toolkit) — genotype-based and reference-free demultiplexing of pooled droplet-based single-cell RNA-seq experiments. demuxlet requires known donor genotypes (VCF/BCF)
Use with AI
Install the MCP server or CLI to instantly fetch demuxlet / freemuxlet (popscle) documentation:
Install command
claude mcp add biocontext7 -- npx @biocontext7/mcpOr share this page: biocontext7.com/tools/demuxletfreemuxlet
Benchmark and compare bioinformatics tools for a given analysis task using published benchmark data (accuracy, runtime, memory), PrecisionFDA and CAMI challenge results, bc7score community metrics, an
2 shared topics • 1 shared operation
DecontX — R/Bioconductor method in the celda package for estimating and removing ambient RNA contamination from droplet-based single-cell RNA-seq data. Uses a Bayesian Dirichlet mixture model over cel
2 shared topics • 1 shared operation
estimate-compute-requirements — predict CPU, memory, wall time, and storage for bioinformatics pipelines given input data size and tool selection. Generates per-step resource tables, platform-specific
2 shared topics • 1 shared operation
scDblFinder — Bioconductor R package for detecting doublets in single-cell RNA-seq data using simulation-based classification with gradient boosting. Identifies neotypic and heterotypic doublets in dr
2 shared topics • 1 shared operation
Seurat — comprehensive R toolkit for single-cell genomics enabling QC, normalization (LogNormalize, SCTransform), feature selection, dimensionality reduction (PCA, UMAP, t-SNE), graph-based clustering
2 shared topics • 1 shared operation