Clingen

Ensembl VEP (Variant Effect Predictor) — annotates genomic variants with gene, transcript, protein, and regulatory consequences using Ensembl's annotation framework. Supports VCF, HGVS, and genomic co

2 shared topics

ClinVar Database — NCBI's public archive of human genetic variant clinical significance. Query via E-utilities REST API (esearch, esummary, efetch, elink) or download bulk data from FTP in XML, VCF, a

1 shared topic • 1 shared operation

Poetry is the Python dependency management and packaging tool for creating reproducible projects with pyproject.toml and poetry.lock. Use this skill for dependency resolution, virtual environment isol

1 shared topic • 1 shared operation

PubMed Database — NCBI's comprehensive biomedical literature database providing free access to over 37 million citations from MEDLINE, life science journals, and online books. Query via E-utilities RE

1 shared topic • 1 shared operation

Zarr — chunked, compressed N-dimensional arrays for Python with cloud-native storage. Provides hierarchical groups, pluggable compression codecs (Blosc, Zstd, Gzip), sharding for large-scale datasets,

1 shared topic • 1 shared operation