Change-O is the Immcantation toolkit for B cell immunoglobulin repertoire analysis. Parse IMGT/IgBLAST V(D)J alignment output into AIRR-format databases with MakeDb.py, cluster sequences into clonotyp
Use with AI
Install the MCP server or CLI to instantly fetch Change-O documentation:
Install command
claude mcp add biocontext7 -- npx @biocontext7/mcpOr share this page: biocontext7.com/tools/change-o
DecontX — R/Bioconductor method in the celda package for estimating and removing ambient RNA contamination from droplet-based single-cell RNA-seq data. Uses a Bayesian Dirichlet mixture model over cel
1 shared topic • 2 shared operations
Giotto Suite — comprehensive R framework for spatial multi-omics analysis supporting 20+ spatial technologies (Visium, MERFISH, Xenium, CosMx, Slide-seq, seqFISH, CODEX, Stereo-seq). Technology-agnost
1 shared topic • 2 shared operations
IGV (Integrative Genomics Viewer) — high-performance Java desktop application for interactive visualization and exploration of genomic data. Supports BAM/CRAM alignments, VCF variants, BED/GFF annotat
1 shared topic • 2 shared operations
NanoPlot — visualization and quality-control tool for Oxford Nanopore long-read sequencing data. Generates read length histograms, quality distribution plots, cumulative yield curves, and alignment id
1 shared topic • 2 shared operations
PRINSEQ++ — high-performance C++ tool for quality control and preprocessing of FASTQ sequencing reads. Filters and trims reads by quality score, length, GC content, sequence complexity (DUST/entropy),
1 shared topic • 2 shared operations