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BAGEL2 — Bayesian Analysis of Gene Essentiality v2 for identifying essential genes from CRISPR/Cas9 knockout screens. Calculates Bayes Factors from fold-change distributions using reference sets of co
Use with AI
Install the MCP server or CLI to instantly fetch BAGEL2 documentation:
Install command
claude mcp add biocontext7 -- npx @biocontext7/mcpOr share this page: biocontext7.com/tools/bagel2
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Use when correcting copy-number bias in CRISPR-Cas9 essentiality screens with CERES. Handles guide-level depletion data from Project Achilles or custom CRISPR knockout screens, integrating segmented c
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CHOPCHOP — web-based and command-line tool for designing optimized CRISPR guide RNAs (sgRNA) and TALENs. Supports Cas9, Cas9 nickase, Cpf1/Cas12a, and Cas13 nuclease systems across 200+ genomes. Provi
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CRISPRscan — sequence-based scoring algorithm for predicting CRISPR/Cas9 sgRNA on-target efficiency. Uses a linear regression model trained on zebrafish injection data to score 20-mer guide sequences
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Telomere biology toolkit for measuring telomere length from sequencing data, analyzing telomere repeat content, detecting ALT (Alternative Lengthening of Telomeres) pathways, and studying telomere str
2 shared topics • 1 shared operation